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Artistic representation of an enzyme adopting a misfolded structure during the folding process.

Read our March issue

This month we have a Meeting Report from the LGBTQ+ STEM Day held last year, a Q+A with Matthew Horwitz of the Synthesis Workshop podcast, and an In Your Element article focussing on cucurbiturils.

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Proud scientists

Kemi Oloyede reflects on the importance of having LGBTQ+ STEM events, and their role in combatting inertia in the scientific community.

research papers for chemistry

Dismantling barriers faced by women in STEM

Governments worldwide are committing more funding for scientific research in the face of the ongoing pandemic and climate crises. However, the funding process must be restructured to remove the barriers arising from conscious and unconscious biases experienced by minoritized groups, including women, and particularly women of colour.

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Working towards a new job

The time between accepting a position as an assistant professor and taking the role is exciting and unique. But how much work is required before you even start? Shira Joudan ponders which tasks are necessary and how many times one should interrupt a very well-deserved break.

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A community that educates itself

Matthew Horwitz, creator of the Synthesis Workshop video podcast, talks to Nature Chemistry about using podcasting as a driver of professional-level education in the chemistry community.

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Stable organolithium gels.

How synonymous mutations alter enzyme structure and function over long timescales

Organogel delivery vehicles for the stabilization of organolithium reagents

Hydrogen atom collisions with a semiconductor efficiently promote electrons to the conduction band

Volume 15 Issue 3

Announcements

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2022 Nobel Prize in Chemistry

The 2022 Nobel Prize in Chemistry has been awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for the development of click chemistry and bioorthogonal chemistry. In recognition of this award, Nature Portfolio presents a collection of research, review and opinion articles that focus on the origins, the development and the future directions inspired by the topic.

Nature Synthesis open for submissions!

Nature Synthesis is open for submissions of original research articles. The journal will publish research, reviews and opinion articles on chemical and materials synthesis as well as enabling technological innovations.

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The COVID-19 pandemic is causing significant disruption and we are very aware that many researchers will have difficulty in meeting the standard timelines for our peer-review process. Please let us know if you need additional time. Our systems will continue to remind you of the original deadlines but we will be highly flexible as required.

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Latest Research articles

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Autonomous and directional flow of water and transport of particles across a subliming dynamic crystal surface

Crystals of hexachlorobenzene have now been shown to support the autonomous motion of water and particulate matter over their surface. Parallel microchannels present at the surface of the crystal gradually widen by sublimation, propelling droplets of condensed ambient water that can also transport microscopic amounts of material such as silver microparticles.

research papers for chemistry

Control of dynamic sp 3 -C stereochemistry

Stereogenic sp 3 -hybridized carbon centres are the principal building blocks of chiral organic molecules. Usually, these centres are configurationally fixed. Now, low-energy pericyclic rearrangements have been used to create rigid cage molecules with fluxional sp 3 -stereochemistry, influencing chiral information transfer. The sp 3 -carbon stereochemistry of the cages is inverted through strain-assisted Cope rearrangements.

research papers for chemistry

Connecting the geometric and electronic structures of the nitrogenase iron–molybdenum cofactor through site-selective 57 Fe labelling

The molybdenum nitrogenase catalytic cofactor is composed of seven high-spin Fe sites making it difficult to study spectroscopically. Now it has been shown that 57 Fe can be incorporated into a single site and that such site-selectively labelled samples provide insights into the cofactor’s electronic structure and the mechanism of biological nitrogen fixation.

research papers for chemistry

Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y

The controlled functionalization of multihydrosilanes is challenging. Now, using a hydrogen-atom-transfer photocatalyst based on neutral eosin Y, a method for the diverse functionalization of hydrosilanes has been developed, enabling the stepwise on-demand decoration of silicon atoms. This approach is distinguished by its atom-, step-, redox- and catalyst-economy, metal-free nature, its versatility (>150 examples), modularity, selectivity and scalability.

research papers for chemistry

Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis

The alkaloids crocagins are derived from a ribosomal peptide through a series of enzymatic post-translational modifications. A combination of biochemistry and structural biology techniques has now been used to elucidate this biosynthetic pathway, propose a mechanism for the formation of the tetracyclic core structure and enable genome mining for related natural products.

research papers for chemistry

Aromatic hexazine [N 6 ] 4− anion featured in the complex structure of the high-pressure potassium nitrogen compound K 9 N 56

Aromatic polynitrogen units can display both high stability and high energy content. A hexazine anion has now been identified in a complex compound, K 9 N 56 , which is formed at high pressures and temperatures under laser-heating in a diamond anvil cell. The [N 6 ] 4− ring is planar and proposed to be aromatic.

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Serial rotation electron diffraction for rapid phase analysis to accelerate materials development

Serial rotation electron diffraction (SerialRED) enables rapid and reliable phase analysis and structure determination of complex polycrystalline materials that cannot be routinely characterized using X-ray diffraction. Five zeolite phases were identified in a single synthesis product by automated screening of hundreds of crystals, demonstrating the power of SerialRED for materials development.

research papers for chemistry

Nanomachines built from multiple components can have functional advantages

Nanomachines are central to life and are becoming an important part of self-regulated nanotechnologies. Inspired by natural self-assembled nanosystems, it has been shown that artificial nanosystems can evolve and adopt regulatory functions upon fragmentation of their structures into multiple components that reassemble to form the same nanostructure.

research papers for chemistry

Mysterious energy losses

The adiabatic approximation is often applied to describe the scattering of molecules or atoms from solid surfaces. Now, unusual energy loss has been observed during the scattering of hyperthermal hydrogen atoms from a single crystalline Ge(111) surface — suggesting the existence of a non-adiabatic mechanism involving electronic interband transitions in the Ge that are induced by the hydrogen atoms.

research papers for chemistry

Organolithium reagents are characterized by their high reactivity towards air and moisture, traditionally requiring strict inert conditions for their handling and utilization. Now, these reagents can be encapsulated within an organogel, enhancing their stability and allowing their use and storage under ambient conditions.

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Colouring by force

Shining light on diselenide bonds.

Selective cycloadditions

Chiral sulfinyls from sulfones

News & Comment

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Cucurbituril curiosities

Rahul Dev Mukhopadhyay and Kimoon Kim consider how cucurbiturils — pumpkin-shaped macrocycles — went from curiosities to compelling cavitands for a host of applications.

research papers for chemistry

Withstanding winter with mushroom therapy

Winter brings a spike in mortality rates, but rather than simply having more parties to divert our attention, Bruce Gibb suggests that perhaps we should be looking to the misunderstood mushroom to give us a boost.

research papers for chemistry

Flammable ice of profit and doom

Methane hydrate clogs pipelines, is difficult to extract profitably, and exists in quantities sufficient to screw up Earth’s climate. Brett Thornton and Christian Stranne consider this confounding cage compound.

research papers for chemistry

No man is an island

Amilra Prasanna (AP) de Silva talks to Nature Chemistry about his path in chemistry, from photochemistry to sodium sensors to logic gates, through connections between people and between two places that share more than it may seem, Sri Lanka and Northern Ireland.

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Rupturing aromaticity by periphery overcrowding

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Control of dynamic sp3-C stereochemistry

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Find Chemistry Research Topics for Your Paper

Updated Aug 2021 Choosing the right topic for a paper is not an easy task, considering that you risk encountering major difficulties down the road if you pick a topic that is too general, too complex or too narrow. To help students like you, we’ve come up with a fresh list of interesting chemistry topics that you can cover in your next paper.

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You can always theorize on anything that you like. You can theorize on basically any field of science, and in some areas, it’s mostly about theory. In chemistry, however, it’s all about blending theory and practice together.

While you can get inspired to become the next big thing in the world of chemistry, and you may be able to theorize something out of this world, if you cannot logically draw it out and put it into practice – it’s not going to be great for your research paper. Fall back on existing studies, think of something unique, and try it out before.

High school chemistry research topics

High-school chemistry is fascinating due to the real-life applications you can discover through experiments and studies. Students who have to write chemistry papers prefer topics that are more practical than abstract. If you want to write a paper and be excited about the results you are going to get, explore our list of research topics for high school students.

Chemistry research topics for college

Chemistry gets more complicated in college, but the rewards are as great as the challenges. Course material usually relates directly to problems or issues of our daily lives. By writing a research paper, you discover the truth behind real-world processes or activities.  Choose from the following topics to write a compelling paper.

Interesting chemistry research topics 

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Chem undergraduates are passionate about their academic discipline, so they enjoy researching intriguing aspects in your field. There’s so much to learn and discover that the real challenge is choosing a topic. If you want to write original papers, check our list. As a professional research paper writing service , we feature research ideas that relate to important issues of modern society. Get your inspiration below.

Organic chemistry research topics

Do you have to write a paper on organic chemistry? This is where you must focus on the structure, properties, composition, or reactions of carbon-containing compounds. This is one of the most rewarding parts of chemistry, where every study leads to a real-life practical solution. Whether you’re buying research paper or writing one by yourself,  choose a topic that you’re passionate about from the examples below.

Inorganic chemistry research topics

Inorganic chemistry covers everything regarding the synthesis and behavior of inorganic chemical compounds. This is where chemical innovation and invention reign. You can focus on your paper in these top research-areas below.

Chemical engineering research topics

Are you a chemical engineering student? Do you want to write a paper that will impress your professor and help you learn more about your field? Explore these intriguing topics.

Computational chemistry research topics

Computational chemistry is a promising research area research for chem scientists. Even if you’re at the beginning of your academic career, these are some challenging, yet approachable topics you can write about in your next research paper.

Analytical chemistry research topics

In your first analytical chemistry class, you discovered that this is the discipline that studies and analyzes matter using various instruments and methods. This is a vast area of knowledge, so if you want to narrow down your interests for a research paper, look below at our list.

Controversial Chemistry Research Topics

While it might not seem like it, the way that our understanding of chemistry evolves can be quite controversial. Here are some high-end unique topics on the controversy of chemistry:

Essential Chemistry Research Topics

Chemistry, along with physics, is one of the essential sciences, so here are some of the essential topics that will get you a broader understanding of the field:

Environmental chemistry research topics

The threat of global warming has led to a new academic discipline, environmental chemistry, which studies the effects of human activity on natural environments and other interesting aspects related to the natural world. Write a paper on a popular topic to arouse your reader's attention.

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Biochemistry research paper topics

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Although enthusiasm for atomic energy has waxed and waned over the decades, Bárbara Pinho finds the question of waste has yet to be solved

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N -heterocyclic carbenes are more than passive spectators

By Jennifer Newton

The practical importance of N -heterocyclic carbenes continues to grow

Stereotypical mad scientist

Turning negative results into positives

By Derek Lowe

Publishing unsuccessful experiments is more important than ever as we try to train machines in chemistry

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How long until papers list an AI as an author?

Artificial intelligence is superior to humans at numerous tasks, but it is still vulnerable to human biases

White papers

Chalkboard office with notes, formulae etc

How catalysis may enable ‘wish-list’ reactions

Sponsored by Sinocompound

Huber Unistat 515 system

Sizing of temperature control units for reactor applications

Sponsored by Huber

A pile of plastic bottles

Evaluating safety and performance of recycled plastics

Sponsored by Waters Corporation

Infrared

Application of chiller technology to laboratory distillations

Silicon Wafer with microchips used in electronics for the fabrication of integrated circuits

Additive quantification in a commercial CMP sample

Testing oil samples in lab glassware

Rapid, direct additive analysis in mineral oils

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The book cover of A taste for poison

Book Club - A Taste for Poison

By Rebecca Trager , Frances Addison , Monserrat Garduño-Castro

Learning about chemistry through poisons and murders

A cover of the book that features a drawing of large green leaves on an orange background. Over the top of the image, large captial letters spell out 'Fresh Banana Leaves'

Book club – Fresh Banana Leaves by Jessica Hernandez

By Enna Guadalupe , Nikki Man , Katrina Krämer

An Indigenous vision for environmental science

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Book club – Racing Green

By Jennifer Newton , Don Carpenetti , Rebecca Trager

Motorsports are saving the world

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Burn: The Misunderstood Science of Metabolism

Delving into the thermodynamics of the human body

An image showing the book cover of The story of CO2

The Story of CO 2 : Big Ideas for a Small Molecule

If you only read one book about climate change this year, make it this one

An image showing the book cover of The light ages

The Light Ages: A Medieval Journey of Discovery

A delightful peek at our roots as scientists

An image showing the book cover of The flavor equation

The Flavor Equation: The Science of Great Cooking Explained + More Than 100 Essential Recipes

Exciting recipes and beautiful photographs, but at the expense for murky science

An image showing the book cover of Strange bedfellows

Strange Bedfellows: Adventures in the Science, History, and Surprising Secrets of STDs

Not your average encyclopaedia of infectious diseases

An image showing the book cover of Handmade

Handmade: A Scientist’s Search for Meaning through Making

A hands-on approach to materials science

Guenter Hans Sauerbrey

Sauerbrey’s crystal microbalance

A creative balance between fields

Calcite birefringence

Malus’s rays

Getting polarisation right despite theorising molecules of light

Object found on burial site near the embalming workshop

Residues from embalming vessels cast new light on ancient Egyptian mummification

Chemists reveal the compounds and sources of embalming treatments

Charles Adolphe Wurtz

Wurtz’s ball tube

Turning fractional distillation into a whole new ball game

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25 Tips to Pick Up the Best Chemistry Research Paper Topics

Lots of people think that chemistry is something distant, connected to the big factory and complicated researches. But everything that surrounds us is chemistry, every atom, molecule and piece of matter is involved in chemical process. You can write literally about chemistry of anything and be completely right.

One of the areas that is popular, understandable and interesting for everyone is food chemistry. Lots of people are wondering what they are eating and how does it influence their well-being. The research paper on food chemistry can explore artificial foods or completely organic ones, because they also are the products of chemical processes. Think about most popular food concerns in your regions and it will make a wonderful topic for your research.

Another interesting variant is chemical innovations. New materials now are capable of things that seemed magical even a decade ago. They are super-light, super-durable and even can substitute some of the living tissues due to the similar chemical properties. Some of these materials are still experimental, so not all the data about them is revealed, but if you manage to connect the inventors and ask them, your research will be outstanding.

Read also: A safe way to buy research papers from trusted service.

The third broad area you may use is the chemistry of the pollution and eliminating the pollution. Humanity pollutes the world around with chemical processes, but they can be reverted or changed to harmless with the help of that very chemistry. The problem of pollution is very acute now, so the research paper that touches it and provides some solutions will be very valuable in the eyes of your audience.

If you need more narrowed samples, feel free to check the list of the topics we gathered for you.

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  10. 25 Chemistry Research Paper Topics

    The research paper on food chemistry can explore artificial foods or completely organic ones, because they also are the products of chemical processes.